Shopify and WordPress serve different e-commerce needs. Shopify is a dedicated e-commerce platform providing hosting, security, and payment processing in one package. It's ideal for businesses wanting a complete solution without technical maintenance. WordPress with WooCommerce offers more flexibility but requires more setup and management.

Shopify includes built-in payment processing, inventory management, and shipping calculators. It handles updates, security, and hosting automatically. WordPress requires separate hosting, SSL certificates, and plugin management but allows complete design and functionality control.

Consider costs: Shopify has monthly fees plus transaction costs, while WordPress has hosting costs plus potential premium plugin expenses. For content-heavy sites, WordPress excels with its blogging capabilities. For pure e-commerce focus, Shopify provides streamlined operations. Evaluate based on technical resources, budget, and specific business needs.